Pachypodium succulentum is a dwarf shrub, which grows 0.6 to 1 m tall, depending on the climate and conditions of the area. The stem is swollen at the base and turnip-shaped, up to ± 200 mm in diameter, and half buried. It produces several branches which grow between 150–600 mm long. The narrow, dark green leaves are alternate, about 20–60 mm long and 10 mm broad, hairy underneath, with recurved margins. The leaves are borne towards the tips of the branches, among brownish spines, 10 mm to 20 mm long. The spines are modified stipules at the base of the leaves, and persist after the leaves have fallen. It has 3 spines, 2 are nearly equal in size, and one is smaller.It produces white to crimson, star-shaped flowers at the tips of the branches in spring and early summer, between September and December. The flowers have a long, nearly cylindrical tube, 10–80 mm long and up to 2 mm in diameter, opening to 5 spreading lobes, 8–18 mm long, the middle of each petal marked with a darker stripe. Many seeds are produced in paired seed pods, the seed with a tuft of whitish hairs at one end.
Pachypodium succulentum is easy to cultivate, and can be propagated by stem cutting and by seeds. Cuttings should be taken while in active growth during the summer growing season, for the best chance of successful rooting. Allow the cutting to dry out for 5 days, before placing them in rooting medium. Sow seeds in spring or early summer, in well-drained soil, and keep warm and damp until germination. Grow Pachypodium succulentum in a full sun position in well-drained soil and take care not to overwater or let it become waterlogged. It is best suited to a region with a dry winter, or it must be kept dry in winter to allow the soil to dry out during its dormant season. It is best suited to sunny, warm, dry and rocky gardens, and in rockeries, and is suitable for containers. This spelucies is not suitable for cold, wet gardens, although it will survive subzero winter temperatures.